| name | supported | description | year | publisher | cloneof | notes |
| amcall | yes | AMCALL (v2.06) | 1982 | MicroCALL Services | | |
| amcalla | yes | AMCALL (v2.06, Alt) | 1982 | MicroCALL Services | amcall | |
| drivec | yes | Drive C: (Rev. F) | 1983 | Drive C: | | |
| mileston | yes | Milestone (Rev 1.09) | 1981 | Organic Software | | |
| interrog | yes | Interrogator | 1984 | Dysan | | |
| microlnk | yes | The Micro Link (v2.3) | 1981 | Wordcraft | | |
| sysconf | yes | Osborne-1 System Confidence Test (v2.04) | 19?? | <unknown> | | |
| sysconfa | yes | Osborne-1 System Confidence Test (v2.04, Alt) | 19?? | <unknown> | sysconf | |
| sysconfb | no | Osborne-1 System Confidence Test (v2.00) | 19?? | <unknown> | sysconf | |
| actcpm | yes | 60K CP/M vers 2.20 for Osborne | 19?? | Australian Computer & Telecommunications | | |
| basic80 | yes | BASIC-80 (Rev. 5.21) | 1981 | Microsoft | | |
| dbase2 | yes | dBase II (v2.3) | 1982 | <unknown> | | |
| mdm740 | yes | MDM740 modem program | 1984 | <unknown> | | |
| cpm22 | yes | 60k CP/M v2.2 | 1981 | Digital Research | | |
| cpm22a | yes | 60k CP/M v2.2 (Alt) | 1981 | Digital Research | cpm22 | |
| utils | yes | Utilities | 19?? | <unknown> | | |
| xutils | yes | Extended Utilities | 19?? | <unknown> | | |
| wordstar | yes | Wordstar (rel. 2.26) | 1981 | Micropro International | | |
| blank | yes | Osborne 1 blank disk | 19?? | <unknown> | | |
| osmosis | no | Osmosis CP/M Disk Emulation System (v1.0) | 1983 | Osmosis Computer | | |
| dddist | no | Double Density Distribution (v1.4) | 1982 | Osmosis Computer | | |
| rt60a | no | RT-60A Real Time Clock Software (v2.7) | 19?? | JG Communications | | |